Sisapronil. Residue Monograph of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), 81st meeting 2015

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dc.date2023-04-27T12:04:20Z
dc.date2023-04-27T12:04:20Z
dc.date2016
dc.date2018-01-10T04:08:37.0000000Z
dc.date.accessioned2026-06-27T23:39:44Z
dc.descriptionSisapronil is a member of the phenylpyrazole class of antiparasitics. It is a long-acting subcutaneous injectable ectoparasiticide for control of cattle ticks. It also aids in the control of bot fly larvae, hornfly and screwworm. Sisapronil binds tightly to ligand-gated chloride channels, in particular those gated by the neurotransmitter gamma-aminobutyric acid (GABA), blocking the pre- and post-synaptic transference of chloride ions through cell membranes in insects or mites, exposed through in gestion or contact. This mechanism of action results in hyperexcitability of the central nervous system and death of the parasites. Sisapronil has been registered for use in Brazil with a withdrawal period of 120 days.
dc.format16 p.
dc.formatapplication/pdf
dc.identifier2664-7451
dc.identifier1817-7077
dc.identifierhttps://openknowledge.fao.org/handle/20.500.14283/BP388E
dc.identifierhttp://www.fao.org/3/a-bp388e.pdf
dc.identifier.urihttp://hdl.handle.net/123456789/287834
dc.languageEnglish
dc.publisherFAO/WHO ;
dc.relationJoint FAO/WHO Expert Committee on Food Additives (JECFA) Monographs
dc.rightsFAO
dc.titleSisapronil. Residue Monograph of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), 81st meeting 2015
dc.titleSisapronil. Residue Monograph of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), 81st meeting 2015
dc.typeDocument

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