Trypanosome population biology - an approach to support the control of drug resistance and integrated trypanosomosis control

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dc.creatorColeman, P.G.
dc.creatorMcDermott, John J.
dc.date2000
dc.date2014-10-31T06:22:20Z
dc.date2014-10-31T06:22:20Z
dc.date.accessioned2026-06-27T16:55:17Z
dc.descriptionThe identification and tracking of sub-populations through time and space are critical to fully understanding the epidemiology of parasitic diseases. However, very little is known about the structure, distribution and dynamics of trypanosome populations in the field. Most laboratory studies that have characterised trypanosomes have concentrated on adapted clones, while in those studies that have applied the characterisation techniques to field samples the number of isolates examined tended to be relatively small. Here, we examine how knowledge of the population biology of trypanosomes could be used to better understand the epidemiology of drug resistance and inform the design of integrated control strategies to manage the spread of drug resistance. Specific areas of research are proposed (e.g. experimental determination of the relative fitness of drug-sensitive and drug-resistant clones) that are important to furthering this knowledge.
dc.identifierhttps://hdl.handle.net/10568/51267
dc.identifier.urihttp://hdl.handle.net/123456789/137104
dc.languageen
dc.publisherEuropean Union
dc.rightsLimited Access
dc.subjecttrypanosomiasis
dc.subjectdisease control
dc.subjecttrypanosomes (phytomonas)
dc.subjectbiology
dc.subjectdrug resistance
dc.titleTrypanosome population biology - an approach to support the control of drug resistance and integrated trypanosomosis control
dc.typeConference Paper

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Instituto Internacional de Investigaciones Pecuarias (ILRI)