Resistance to endoparasites in small ruminants: Immunological considerations
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International Livestock Centre for Africa
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The paper focusses on the genetic control of immunoresponsiveness in Trichostrongylus selection lines. It discusses results from other selection programmes in which some characterisation of the immune - response system has been undertaken. It is Reported that some aspects of this work may not have direct relevance to African conditions. Topics of discussion include modelling, mechanistic basis of the various selection flocks, area of research in Trichostrongylus flock, testing for responsiveness, response to selection, major immune responses, predictive markers with resistance, specificity of selection, and ability of parasites to adapt to with stand the lost immune responses. Results show that high responders have greater protection than low responders against anthelmintic - resistant T. colubriformis, T. rugatus, and Ostertagia circumcincta.
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sheep, goats, genetic resistance, parasitoses, models, genetic markers, trichostrongylus, immune response