In vitro models as tools for screening the relative bioavailabilities of provitamin A carotenoids in foods

dc.creatorFailla, Mark L.
dc.creatorChitchumroonchokchai, Chureeporn
dc.date2005
dc.date2024-11-13T22:02:51Z
dc.date2024-11-13T22:02:51Z
dc.date.accessioned2026-06-27T15:22:48Z
dc.descriptionThis review is organized as follows. First, the characteristics of the digestion and absorption and the metabolism of vitamin A and carotenoids are briefly discussed in Sections 2 and 3, respectively. The numerous factors that affect carotenoid bioavailability are considered in Section 4. Section 5 first presents an overview of the techniques used to determine the relative bioavailabilities of carotenoids in vivo, and then describes the biochemical and cellular methods that are used to investigate the gastrointestinal processes associated with the accessibility and cellular transport of carotenoids. Key results from studies employing in vitro methods are systematically reviewed in Section 6. Finally Section 7 directly compares the findings of in vivo and in vitro studies and, on the basis of this comparison, proposes the use of simulated digestion and Caco-2 cells as tools for the initial screening for the relative bioavailability of provitamin A carotenoids from staple foods prepared according to local methods.
dc.formatapplication/pdf
dc.identifierhttps://hdl.handle.net/10568/159709
dc.identifier.urihttp://hdl.handle.net/123456789/102633
dc.languageen
dc.publisherInternational Food Policy Research Institute
dc.publisherInternational Center for Tropical Agriculture
dc.rightsOpen Access
dc.sourceFailla, Mark L.; and Chitchumroonchokchai, Chureeporn. 2005. In vitro models as tools for screening the relative bioavailabilities of provitamin A carotenoids in foods. HarvestPlus Technical Monograph Series 3. Washington, DC and Cali, Columbia: International Food Policy Research Institute and International Center for Tropical Agriculture. https://hdl.handle.net/10568/159709
dc.subjectretinol
dc.subjectbioavailability
dc.subjecttrace elements
dc.subjectdigestion
dc.subjectprovitamins
dc.subjectcarotenoids
dc.titleIn vitro models as tools for screening the relative bioavailabilities of provitamin A carotenoids in foods
dc.typeBook

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