Determining a global mid-upper arm circumference cut-off to assess underweight in adults (men and non-pregnant women)

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dc.creatorTang, Alice M.
dc.creatorChung, Mei
dc.creatorDong, Kimberly R.
dc.creatorBahwere, Paluku
dc.creatorBose, Kaushik
dc.creatorNguyen, Phuong Hong
dc.date2020-09-01
dc.date2024-05-22T12:11:14Z
dc.date2024-05-22T12:11:14Z
dc.date.accessioned2026-06-27T15:35:32Z
dc.descriptionTo determine if a global mid-upper arm circumference (MUAC) cut-off can be established to classify underweight in adults (men and non-pregnant women).We conducted an individual participant data meta-analysis (IPDMA) to explore the sensitivity (SENS) and specificity (SPEC) of various MUAC cut-offs for identifying underweight among adults (defined as BMI < 18·5 kg/m2). Measures of diagnostic accuracy were determined every 0·5 cm across MUAC values from 19·0 to 26·5 cm. A bivariate random effects model was used to jointly estimate SENS and SPEC while accounting for heterogeneity between studies. Various subgroup analyses were performed.Twenty datasets from Africa, South Asia, Southeast Asia, North America and South America were included.All eligible participants from the original datasets were included.The total sample size was 13 835. Mean age was 32·6 years and 65 % of participants were female. Mean MUAC was 25·7 cm, and 28 % of all participants had low BMI (<18·5 kg/m2). The area under the receiver operating characteristic curve for the pooled dataset was 0·91 (range across studies 0·61–0·98). Results showed that MUAC cut-offs in the range of ≤23·5 to ≤25·0 cm could serve as an appropriate screening indicator for underweight.MUAC is highly discriminatory in its ability to distinguish adults with BMI above and below 18·5 kg/m2. This IPDMA is the first step towards determining a global MUAC cut-off for adults. Validation studies are needed to determine whether the proposed MUAC cut-off of 24 cm is associated with poor functional outcomes.
dc.identifierhttps://hdl.handle.net/10568/142877
dc.identifier.urihttp://hdl.handle.net/123456789/108795
dc.languageen
dc.publisherCambridge University Press
dc.relationhttps://hdl.handle.net/10568/147448
dc.rightsLimited Access
dc.sourceTang, Alice M.; Chung, Mei; Dong, Kimberly R.; Bahwere, Paluku; Bose, Kaushik; Nguyen, Phuong Hong; et al. 2020. Determining a global mid-upper arm circumference cut-off to assess underweight in adults (men and non-pregnant women). Public Health Nutrition 23(17): 3104 - 3113. https://doi.org/10.1017/S1368980020000397
dc.subjectdata analysis
dc.subjectgender
dc.subjectbody mass index
dc.subjectadults
dc.subjectnutrition surveillance
dc.subjectthinness
dc.subjectmalnutrition
dc.subjectnutrition
dc.subjectarm circumference
dc.titleDetermining a global mid-upper arm circumference cut-off to assess underweight in adults (men and non-pregnant women)
dc.typeJournal Article

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Instituto Internacional de Investigación sobre Políticas Alimentarias (IFPRI)