A Brief Review on the Regulatory Roles of MicroRNAs in Cystic Diseases and Their Use as Potential Biomarkers

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dc.creatorRuiz-Manriquez, Luis M.
dc.creatorLedesma Pacheco, Schoenstatt Janin
dc.creatorMedina-Gomez, Daniel
dc.creatorUriostegui-Pena, Andrea G.
dc.creatorEstrada-Meza, Carolina
dc.creatorBandyopadhyay, Anindya
dc.creatorPathak, Surajit
dc.creatorBanerjee, Antara
dc.creatorChakraborty, Samik
dc.creatorSrivastava, Aashish
dc.creatorPaul, Sujay
dc.date2022-01-22
dc.date2026-06-10T06:06:06Z
dc.date.accessioned2026-06-27T04:12:59Z
dc.descriptionmiRNAs are small endogenous conserved non-coding RNA molecules that regulate posttranscriptional gene expression through mRNA degradation or translational inhibition, modulating nearly 60% of human genes. Cystic diseases are characterized by the presence of abnormal fluidfilled sacs in the body, and though most cysts are benign, they can grow inside tumors and turn malignant. Recent evidence has revealed that the aberrant expression of a number of miRNAs present in extracellular fluids, including plasma or serum, urine, saliva, follicular fluid, and semen, contribute to different cystic pathologies. This review aims to describe the role of different miRNAs in three worldwide relevant cystic diseases: polycystic ovarian syndrome (PCOS), polycystic kidney disease (PKD), and pancreatic cyst tumors (PCTs), as well as their potential use as novel biomarkers.
dc.formatapplication/pdf
dc.identifierhttps://hdl.handle.net/10568/183279
dc.identifier.urihttp://hdl.handle.net/123456789/25403
dc.languageen
dc.publisherMDPI
dc.rightsOpen Access
dc.sourceRuiz-Manriquez, Luis M., Schoenstatt Janin Ledesma Pacheco, Daniel Medina-Gomez, Andrea G. Uriostegui-Pena, Carolina Estrada-Meza, Anindya Bandyopadhyay, Surajit Pathak et al. "A brief review on the regulatory roles of MicroRNAs in cystic diseases and their use as potential biomarkers." Genes 13, no. 2 (2022): 191.
dc.subjectmicroRNA
dc.subjectbiomarkers
dc.subjectRNA
dc.subjectgene expression
dc.subjectcysts
dc.subjectgene expression regulation
dc.titleA Brief Review on the Regulatory Roles of MicroRNAs in Cystic Diseases and Their Use as Potential Biomarkers
dc.typeJournal Article

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Instituto Internacional de Investigación del Arroz (IRRI)