Evaluation of oraquick® HIV-1/2 as oral rapid test

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dc.creatorNkenfou, C.N.
dc.creatorKembou, J.E.
dc.creatorTemgoua, E.S.
dc.creatorDjikeng, Appolinaire
dc.creatorMouafo, L.M.
dc.creatorNdzie, E.N.
dc.creatorDonkam, I.
dc.creatorColizzi, V.
dc.creatorSanouSobze, M.
dc.date2013
dc.date2015-09-30T10:55:51Z
dc.date2015-09-30T10:55:51Z
dc.date.accessioned2026-06-27T17:03:19Z
dc.descriptionAs Cameroon scales up its national HIV/AIDS control program, evaluating the performance of commercially available tests for accurate and cost effective diagnostics becomes essential. A cross-sectional study assessed the performance of an HIV oral rapid test. A total of 1520 participants consented to participate in the study. After counselling, they were tested for HIV using the national algorithm followed by OraQuick. Results of the national algorithm were compared to those of OraQuick, for sensitivity, specificity, positive predictive and negative predictive values. 62% of participants were male, and 1% was reported HIV-positive following the national algorithm. The OraQuick test had 93% sensitivity, 99% specificity, 99.93% NPV and 90% PPV (95% CI, Kappa 0.965). Though more expensive (2-6x) compared to the national algorithm tests, oral mucosal transudate-based test demonstrated good performance. Therefore, it could be implemented in resource constrained settings if subsidized and could increase participation since less invasive with no blood accident exposure.
dc.identifierhttps://hdl.handle.net/10568/68343
dc.identifier.urihttp://hdl.handle.net/123456789/140899
dc.languageen
dc.publisherAfrican Journals Online
dc.rightsOpen Access
dc.sourceNkenfou, C.N., Kembou, J.E., Temgoua, E.S., Djikeng, A., Mouafo, L.M., Ndzie, E.N., Donkam, I., Colizzi, V. and SanouSobzé, M. 2013. Evaluation of Oraquick® HIV-1/2 as oral rapid test. African Journal of Infectious Diseases 7: 27-30.
dc.subjecthuman diseases
dc.subjecthealth
dc.titleEvaluation of oraquick® HIV-1/2 as oral rapid test
dc.typeJournal Article

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Instituto Internacional de Investigaciones Pecuarias (ILRI)