Physicochemical and toxicity investigation of chitosan-based dsRNA nanocarrier formation.

Vista sencilla de ítem
dc.contributorMAICON S. PETRÔNIO, UNESP
dc.contributorTAIS T. BARROS-ALEXANDRINO
dc.contributorALINE M. F. LIMA, UNESP
dc.contributorODILIO BENEDITO GARRIDO DE ASSIS, CNPDIA
dc.contributorALICE KAZUKO INOUE NAGATA, CNPH
dc.contributorERICH YUKIO TEMPEL NAKASU, CNPH
dc.contributorMARCIO J. TIERA, UNESP
dc.contributorLUCIMEIRE PILON, CNPH.
dc.creatorPETRÔNIO, M. S.
dc.creatorBARROS-ALEXANDRINO, T. T.
dc.creatorLIMA, A. M. F.
dc.creatorASSIS, O. B. G. de
dc.creatorINOUE-NAGATA, A. K.
dc.creatorNAKASU, E. Y. T.
dc.creatorTIERA, M. J.
dc.creatorPILON, L.
dc.date2021-11-18T15:01:13Z
dc.date2021-11-18T15:01:13Z
dc.date2021-11-18
dc.date2022
dc.date.accessioned2026-07-07T04:08:16Z
dc.descriptionThus, the present study is focused on the chitosan-dsRNA interactions and the physicochemical properties of the dsRNA-loaded nanoparticles, including cytotoxicity and hemolysis assays. dsRNA molecules homologous to a partial genome of the phytopathogenic tomato mosaic virus (ToMV) were used as the model virus. The combination of chitosan's antimicrobial properties and its delivery capability provides a potential for ds-RNA-nanoparticles to deliver dsRNA as a tool for virus disease control in crops.
dc.identifierBiointerface Research in Applied Chemistry, v. 12, n. 4, p. 5266-5279, 2022.
dc.identifier2069-5837
dc.identifierhttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1136285
dc.identifierhttps://doi.org/10.33263/BRIAC124.52665279
dc.identifier.urihttp://hdl.handle.net/123456789/452618
dc.languageeng
dc.rightsopenAccess
dc.subjectTomato mosaic virus
dc.subjectDouble-stranded RNA
dc.subjectLettuce
dc.subjectRNA interference
dc.titlePhysicochemical and toxicity investigation of chitosan-based dsRNA nanocarrier formation.
dc.typeArtigo de periódico

Archivos

Colecciones

Embrapa Hortalizas (CNPH)