The use of different progestin devices in ovarian stimulation protocol affects gene expression in sheep cumulus-oocyte complexes (COC).

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dc.contributorUniversidade Federal Fluminense (UFF) - Nitéroi, RJ, Brazil; Jeferson Ferreira da Fonseca, CNPC.
dc.creatorBRAGANÇA, G. M.
dc.creatorBATISTA, R. I. T. P.
dc.creatorSOUZA, C. V.
dc.creatorSANTOS, J. D. R.
dc.creatorARASHIRO, E. K. N.
dc.creatorFONSECA, J. F. da
dc.creatorBRANDÃO, F. Z.
dc.creatorSOUZA-FABJAN, J. M. G.
dc.date2018-09-08T00:29:09Z
dc.date2018-09-08T00:29:09Z
dc.date2018-09-06
dc.date2018
dc.date2019-09-23T11:11:11Z
dc.date.accessioned2026-07-01T00:21:09Z
dc.descriptionProgesterone (P4) and its analogues (progestins) are commonly used in estrus synchronization protocols and to hold the LH surge during ovarian stimulation to allow oocyte recovery in live donor ewes. However, recent evidence suggests that some progestins may have a deleterious effect on embryo quality after long-term use. Thus, the present study aimed to evaluate the effect of two progestin devices used during ovarian stimulation on the COC quality in donor ewes. In conclusion, the progestin device alters the expression of genes related to quality and the steroidogenesis pathway in fully-grown COCs, and the use of a natural P4 device may improve the development competence of COCs. Further studies including IVP are necessary to confirm our findings.
dc.identifierAnimal Reprodroduction, v. 15, n. 3, p. 591, Jul./Sept. 2018. Abstracts A276E. Edição dos Proceedings of the 34rd Meeting of the Association of Embryo Transfer in Europe (AETE); Nantes, France, September 7th and 8th, 2018.
dc.identifierhttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1095158
dc.identifier.urihttp://hdl.handle.net/123456789/402393
dc.languageeng
dc.rightsopenAccess
dc.subjectOvino
dc.subjectReprodução Animal
dc.subjectTransferência de Embrião
dc.subjectSheep
dc.subjectOocytes
dc.subjectProgestogen receptors
dc.subjectSteroid hormones
dc.subjectEmbryo transfer
dc.subjectEwes
dc.titleThe use of different progestin devices in ovarian stimulation protocol affects gene expression in sheep cumulus-oocyte complexes (COC).
dc.typeResumo em anais e proceedings

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