Genomic reference resource for African cattle: Genome sequences and high-density array variants

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dc.creatorTijjani, Abdulfatai
dc.creatorKambal, Sumaya
dc.creatorTerefe, E.
dc.creatorNjeru, Regina
dc.creatorOgugo, Moses
dc.creatorNdambuki, G.
dc.creatorMissohou, A.
dc.creatorTraore, A.
dc.creatorSalim, B.
dc.creatorEzeasor, C.
dc.creatorHirwa, C.D.
dc.creatorObishakin, E.T.
dc.creatorDiallo, B.
dc.creatorTalaki, E.
dc.creatorAbdoukarim, I.Y.
dc.creatorNash, O.
dc.creatorOsei-Amponsah, R.
dc.creatorRavaorimanana, S.
dc.creatorIssa, Y.
dc.creatorZegeye, T.
dc.creatorMukasa, C.
dc.creatorTiambo, Christian K.
dc.creatorPrendergast, J.G.D.
dc.creatorKemp, Stephen J.
dc.creatorHan Jianlin
dc.creatorMarshall, Karen
dc.creatorHanotte, Olivier H.
dc.date2024
dc.date2024-08-13T18:38:54Z
dc.date2024-08-13T18:38:54Z
dc.date.accessioned2026-06-27T17:19:59Z
dc.descriptionThe diversity in genome resources is fundamental to designing genomic strategies for local breed improvement and utilisation. These resources also support gene discovery and enhance our understanding of the mechanisms of resilience with applications beyond local breeds. Here, we report the genome sequences of 555 cattle (208 of which comprise new data) and high-density (HD) array genotyping of 1,082 samples (537 new samples) from indigenous African cattle populations. The new sequences have an average genome coverage of ~30X, three times higher than the average (~10X) of the over 300 sequences already in the public domain. Following variant quality checks, we identified approximately 32.3 million sequence variants and 661,943 HD autosomal variants mapped to the Bos taurus reference genome (ARS-UCD1.2). The new datasets were generated as part of the Centre for Tropical Livestock Genetics and Health (CTLGH) Genomic Reference Resource for African Cattle (GRRFAC) initiative, which aspires to facilitate the generation of this livestock resource and hopes for its utilisation for complete indigenous breed characterisation and sustainable global livestock improvement.
dc.identifierhttps://hdl.handle.net/10568/151675
dc.identifier.urihttp://hdl.handle.net/123456789/149138
dc.languageen
dc.publisherSpringer
dc.rightsOpen Access
dc.sourceTijjani, A., Kambal, S., Terefe, E., Njeru, R., Ogugo, M., Ndambuki, G., Missohou, A., Traore, A., Salim, B., Ezeasor, C., Hirwa, C.D., Obishakin, E.T., Diallo, B., Talaki, E., Abdoukarim, I.Y., Nash, O., Osei-Amponsah, R., Ravaorimanana, S., Issa, Y., Zegeye, T., Mukasa, C., Tiambo, C., Prendergast, J.G.D., Kemp, S.J., Jianlin Han, Marshall, K. and Hanotte, O. 2024. Genomic reference resource for African cattle: Genome sequences and high-density array variants. Scientific Data 11: 801.
dc.subjectcattle
dc.subjectgenomics
dc.subjectlivestock
dc.titleGenomic reference resource for African cattle: Genome sequences and high-density array variants
dc.typeJournal Article

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Instituto Internacional de Investigaciones Pecuarias (ILRI)