Resources available from the African Trypanosome Genome Project

Melville, S.E.; Majiwa, Phelix A.O.; Donelson, J.E.

Resources available from the African Trypanosome Genome Project

Autores

Melville, S.E.

Majiwa, Phelix A.O.

Donelson, J.E.

Editor

Elsevier

Descripción

During its first two years, the African trypanosome genome project, funded in part by the UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR), has concentrated on three fundamental areas: (1) gene discovery by single-pass sequencing of cDNAs to produce expressed sequence tags (ESTs): (2) definition of the karyotype of several stocks of Trypanosoma brucei using ESTs: and (3) hybridization of cDNA clones to a bacteriophage Pl library containing T. brucei genomic DNA. A central tenet of the genome project is the availability of resources to all. To this end, data are deposited in public databases and on the worldwide web site* prior to formal publication where appropriate, and clones may be requested from the genome project laboratories.