Serum Metabolomic Profiling in Healthy Dogs Supplemented with Increasing Levels of Purified Beta-1,3/1,6-Glucans.
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Simple Summary: Diet plays a crucial role in the health of dogs, and researchers are constantly exploring ways to improve nutrition through dietary supplements. This study investigated how beta-1,3/1,6-glucans, a nutraceutical known for its potential immune and gut health benefits, affect the metabolism of healthy dogs. Eight dogs participated in a controlled experiment using a double Latin square design, ensuring that each animal received all diet treatments in a balanced way. This study lasted a total of 140 days, divided into four experimental periods of 35 days each. The dogs were fed diets with different amounts of beta-glucans (0.0%, 0.07%, 0.14%, and 0.28%), and blood samples were collected at the end of each period to analyze metabolic changes. The results showed that certain levels of beta-glucans (0.07% and 0.14%) had a greater impact on metabolism, particularly in pathways related to amino acids and energy production. These findings help us to better understand how this supplement interacts with a dog’s body and could contribute to the development of more tailored and beneficial diets for pets. Further research is needed to explore the long-term effects and practical applications of beta-glucan supplementation in pet nutrition
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Canine, Nutraceuticals, Omics sciences, Supplementation