Effects of anthocyanin on intestinal health: a systematic review.

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dc.contributorTHAÍSA AGRIZZI VEREDIANO, Universidade Federal de Viçosa; HÉRCIA STAMPINI DUARTE MARTINO, Universidade Federal de Viçosa; MARIA CRISTINA DIAS PAES, CNPMS; ELAD TAKO, Cornell University.
dc.creatorVEREDIANO, T. A.
dc.creatorMARTINO, H. S. D.
dc.creatorPAES, M. C. D.
dc.creatorTAKO, E.
dc.date2021-05-07T13:32:25Z
dc.date2021-05-07T13:32:25Z
dc.date2021-05-07
dc.date2021
dc.date.accessioned2026-07-07T05:24:43Z
dc.descriptionIntestinal health relies on the association between the mucosal immune system, intestinal barrier and gut microbiota. Bioactive components that affect the gut microbiota composition, epithelial physical barrier and intestinal morphology were previously studied. The current systematic review evaluated evidence of anthocyanin effects and the ability to improve gut microbiota composition, their metabolites and parameters of the physical barrier; this was conducted in order to answer the question: ?Does food source or extract of anthocyanin promote changes on intestinal parameters??. The data analysis was conducted following the PRISMA guidelines with the search performed at PubMed, Cochrane and Scopus databases for experimental studies, and the risk of bias was assessed by the SYRCLE tool. Twenty-seven studies performed in animal models were included, and evaluated for limitations in heterogeneity, methodologies, absence of information regarding allocation process and investigators? blinding. The data were analyzed, and the anthocyanin supplementation demonstrated positive effects on intestinal health. The main results identified were an increase of Bacteroidetes and a decrease of Firmicutes, an increase of short chain fatty acids production, a decrease of intestinal pH and intestinal permeability, an increase of the number of goblet cells and tight junction proteins and villi improvement in length or height. Thus, the anthocyanin supplementation has a potential effect to improve the intestinal health. PROSPERO (CRD42020204835).
dc.identifierNutrients, v. 13, 1331, 2021.
dc.identifierhttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1131723
dc.identifierhttps://doi.org/10.3390/nu13041331
dc.identifier.urihttp://hdl.handle.net/123456789/490281
dc.languagepor
dc.rightsopenAccess
dc.subjectMicrobiota
dc.subjectPolifenóis
dc.subjectBarreira intestinal
dc.subjectSaúde intestinal
dc.subjectAntocianina
dc.titleEffects of anthocyanin on intestinal health: a systematic review.
dc.typeArtigo de periódico

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