Genome-wide association study on growth traits in Colombian creole breeds and crossbreeds with Zebu cattle

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dc.audienceInvestigador
dc.coverageColombia
dc.creatorMartínez, Rodrigo
dc.creatorM Rocha, Juan Felipe
dc.creatorGómez, Y
dc.date2025-03-03T16:18:55Z
dc.date2025-03-03T16:18:55Z
dc.date2014-08
dc.date2014
dc.date.accessioned2026-06-27T04:39:35Z
dc.descriptionWhole genome selection represents an important tool for improving parameters related to the production of livestock. In order to build genomic selection indexes within a particular breed, it is important to identify polymorphisms that have the most significant association with a desired trait. A genome-wide marker association approach based on the Illumina BovineSNP50 BeadChipTM was used to identify genomic regions affecting birth weight (BW), weaning weight (WW), and daily weight gain (DWG) in purebred and crossbred creole cattle populations. We genotyped 654 individuals of Blanco Orejinegro (BON), Romosinuano (ROMO) and Cebú breeds and the crossbreeds BON x Cebú and ROMO x Cebú, and tested 5 genetic control models. In total, 85 single nucleotide polymorphisms (SNPs) were related (P < 0.05) to the 3 evaluated traits; BW was associated with the highest number of SNPs. For statistical false-positive correction, Bonferroni correction was used. From the results, we identified 7, 6, and 4 SNPs with strong associations with BW, WW, and DWG, respectively. Many of these SNPs were located on important coding regions of the bovine genome; their ontology and interactions are discussed herein. The results could contribute to the identification of genes involved in the physiology of beef cattle growth and the development of new strategies for breeding management via genomic selection to improve the productivity of creole cattle herds.
dc.descriptionGanadería bovina
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dc.formatapplication/pdf
dc.identifierhttps://www.researchgate.net/publication/265055591_Genome-wide_association_study_on_growth_traits_in_Colombian_creole_breeds_and_crossbreeds_with_Zebu_cattle
dc.identifierhttp://hdl.handle.net/20.500.12324/40743
dc.identifierhttp://dx.doi.org/10.4238/2014.August.25.5
dc.identifierreponame:Biblioteca Digital Agropecuaria de Colombia
dc.identifierinstname:Corporación colombiana de investigación agropecuaria AGROSAVIA
dc.identifier.urihttp://hdl.handle.net/123456789/34536
dc.languageeng
dc.publisherResearchGate
dc.relationGenetics and Molecular Research
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dc.rightsAttribution-NonCommercial-ShareAlike 4.0 International
dc.rightshttp://creativecommons.org/licenses/by-nc-sa/4.0/
dc.sourceGenetics and Molecular Research; Vol. 13, Núm. 3 (2014): Genetics and Molecular Research (Aug.);p. 6420-6432.
dc.subjectGenética y mejoramiento animal - L10
dc.subjectCebú
dc.subjectRaza mixta
dc.subjectCruzamiento
dc.subjectGenetista
dc.subjectGanadería y especies menores
dc.subjecthttp://aims.fao.org/aos/agrovoc/c_8507
dc.subjecthttp://aims.fao.org/aos/agrovoc/c_24053
dc.subjecthttp://aims.fao.org/aos/agrovoc/c_1976
dc.subjecthttp://aims.fao.org/aos/agrovoc/c_3221
dc.thumbnailhttps://repository.agrosavia.co/bitstreams/c605c25a-c165-469c-9e08-e1dc99ec04e9/download
dc.titleGenome-wide association study on growth traits in Colombian creole breeds and crossbreeds with Zebu cattle
dc.titleGenome-wide association study on growth traits in Colombian creole breeds and crossbreeds with Zebu cattle
dc.typeArtículo científico

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