Economic Benefit of Tuberculosis Control
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World Bank, Washington, DC
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Tuberculosis is the most important
infectious cause of adult deaths after HIV/AIDS in low- and
middle-income countries. This paper evaluates the economic
benefits of extending the World Health Organization's
DOTS Strategy (a multi-component approach that includes
directly observed treatment, short course chemotherapy and
several other components) as proposed in the Global Plan to
Stop TB, 2006-2015. The authors use a model-based approach
that combines epidemiological projections of averted
mortality and economic benefits measured using value of
statistical life for the Sub-Saharan Africa region and the
22 high-burden, tuberculosis-endemic countries in the world.
The analysis finds that the economic benefits between 2006
and 2015 of sustaining DOTS at current levels relative to
having no DOTS coverage are significantly greater than the
costs in the 22 high-burden, tuberculosis-endemic countries
and the Africa region. The marginal benefits of implementing
the Global Plan to Stop TB relative to a no-DOTS scenario
exceed the marginal costs by a factor of 15 in the 22
high-burden endemic countries, a factor of 9 (95% CI, 8-9)
in the Africa region, and a factor of 9 (95% CI, 9-10) in
the nine high-burden African countries. Uncertainty analysis
shows that benefit-cost ratios of the Global Plan strategy
relative to sustained DOTS were unambiguously greater than
one in all nine high-burden countries in Africa and in
Afghanistan, Pakistan, and Russia. Although HIV curtails the
effect of the tuberculosis programs by lowering the life
expectancy of those receiving treatment, the benefits of the
Global Plan are greatest in African countries with high
levels of HIV.
Palabras clave
ADULT MORTALITY, AGED, AGRICULTURAL DEVELOPMENT, AGRICULTURAL PRODUCTION, AIDS EPIDEMIC, BASIC EDUCATION, BLUEPRINT, BURDEN OF DISEASE, CAUSES OF DEATH, CHEMOTHERAPY, CHILD DEVELOPMENT, CHRONIC DISEASE, COMPLICATIONS, COUNSELING, CULTURAL CHANGE, DEATH RATE, DEATH RATES, DEMOGRAPHIC TRANSITION, DEVELOPING COUNTRIES, DIAGNOSTICS, DIET, DISABILITY, DISEASE, DISEASE BURDEN, DISEASE CONTROL, DISEASE OF POVERTY, DISEASE TRANSMISSION, DRUG RESISTANCE, DRUGS, ECONOMIC GROWTH, ECONOMIC PROSPERITY, ENDEMIC COUNTRIES, ENVIRONMENTAL PROTECTION, EPIDEMIC, EPIDEMICS, EPIDEMIOLOGISTS, EPIDEMIOLOGY, EQUILIBRIUM, EXISTING POPULATION, EXPENDITURES, FAMILIES, FAMILY MEMBERS, FERTILITY, FORECASTS, FUTURE GENERATIONS, GLOBAL HEALTH, HEALTH ECONOMICS, HEALTH INTERVENTIONS, HEALTH POLICY, HEALTH SECTOR, HEALTH SERVICES, HEALTH STATUS, HEALTH SYSTEMS, HIV, HIV TESTING, HOUSEHOLD INCOME, HUMAN CAPITAL, HUMAN DEVELOPMENT, HUMAN POPULATION, ILLNESS, IMMUNODEFICIENCY, INFECTION, INFECTIONS, INFECTIOUS DISEASES, INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, INTERVENTION, INVESTMENT IN CHILDREN, IRON, JOURNAL OF MEDICINE, LABOR MARKET, LABOR SUPPLY, LIFE EXPECTANCY, LIVING CONDITIONS, LIVING STANDARDS, LONGER LIFE, LONGEVITY, LOW-INCOME COUNTRIES, LOW-INCOME COUNTRY, LUNG DISEASE, M. BOVIS, MALARIA, MALNUTRITION, MARKETING, MEDICAL RESEARCH, MEDICINE, MIGRATION, MILLENNIUM DEVELOPMENT GOALS, MINISTRY OF HEALTH, MORBIDITY, MORBIDITY AND MORTALITY, MORTALITY, MORTALITY DECLINE, MORTALITY DECLINES, MORTALITY RATE, MORTALITY REDUCTIONS, MORTALITY RISK, NUMBER OF DEATHS, NUTRITION, PACIFIC REGION, PATIENTS, POLICY RESEARCH, POLICY RESEARCH WORKING PAPER, POOR HEALTH, PREMATURE DEATH, PREVALENCE, PROBABILITY, PROGRESS, PUBLIC HEALTH, PUBLIC HEALTH PROGRAMS, QUALITY OF HEALTH, QUALITY OF LIFE, REMITTANCES, RESOURCE CONSTRAINTS, RESPECT, RISK FACTORS, RISK OF DEATH, RISK OF INFECTION, RISK-TAKING BEHAVIOR, RISKY BEHAVIOR, SCHOOL CHILDREN, SECONDARY SCHOOL, SEX, SOCIAL MOBILIZATION, SUB-SAHARAN AFRICA, SYNDROME, TB, TB CONTROL, TOBACCO, TRANSMISSION OF INFECTION, TRANSMISSION RATES, TREATMENT, TUBERCULOSIS, TUBERCULOSIS CONTROL, UNEMPLOYMENT, UNPROTECTED SEX, VACCINE, VACCINES, WESTERN EUROPE, WORKERS, WORLD HEALTH ORGANIZATION, YOUNG ADULTS
