Wheat Panache: A pangenome graph database representing presence–absence variation across sixteen bread wheat genome

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dc.creatorBayer, Philipp E.
dc.creatorPetereit, Jakob
dc.creatorDurant, Éloi
dc.creatorMonat, Cécile
dc.creatorRouard, Mathieu
dc.creatorHu, Haifei
dc.creatorChapman, Brett
dc.creatorLi, Chengdao
dc.creatorCheng, Shifeng
dc.creatorBatley, Jacqueline
dc.creatorEdwards, David
dc.date2022-09
dc.date2022-05-31T10:43:23Z
dc.date2022-05-31T10:43:23Z
dc.date.accessioned2026-06-27T13:24:06Z
dc.descriptionBread wheat (Triticum aestivum L.) is one of humanity's most important staple crops, characterized by a large and complex genome with a high level of gene presence–absence variation (PAV) between cultivars, hampering genomic approaches for crop improvement. With the growing global population and the increasing impact of climate change on crop yield, there is an urgent need to apply genomic approaches to accelerate wheat breeding. With recent advances in DNA sequencing technology, a growing number of high-quality reference genomes are becoming available, reflecting the genetic content of a diverse range of cultivars. However, information on the presence or absence of genomic regions has been hard to visualize and interrogate because of the size of these genomes and the lack of suitable bioinformatics tools. To address this limitation, we have produced a wheat pangenome graph maintained within an online database to facilitate interrogation and comparison of wheat cultivar genomes. The database allows users to visualize regions of the pangenome to assess PAV between bread wheat genomes.
dc.formatapplication/pdf
dc.identifierhttps://hdl.handle.net/10568/119697
dc.identifier.urihttp://hdl.handle.net/123456789/58248
dc.languageen
dc.publisherWiley
dc.rightsOpen Access
dc.sourceBayer, P.E.; Petereit, J.; Durant, É.; Monat, C.; Rouard, M.; Hu, H.; Chapman, B.; Li, C.; Cheng, S.; Batley, J.; Edwards, D. (2022) Wheat Panache: A pangenome graph database representing presence–absence variation across sixteen bread wheat genome. The Plant Genome, Online first paper (29 May 2022). ISSN: 1940-3372
dc.subjectgenomes
dc.subjectgenetic databases
dc.subjectvarieties
dc.subjectgenomas
dc.subjectbase de datos de recursos genéticos
dc.subjectvariedades
dc.subjectgenetics
dc.titleWheat Panache: A pangenome graph database representing presence–absence variation across sixteen bread wheat genome
dc.typeJournal Article

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