Current Understanding of Feather Keratin and Keratinase and Their Applications in Biotechnology

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dc.creatorMoktip, Thanakorn
dc.creatorSalaipeth, Lakha
dc.creatorCope, Ana Eusebio
dc.creatorTaherzadeh, Mohammad J.
dc.creatorWatanabe, Takashi
dc.creatorPhitsuwan, Paripok
dc.date2025-01-29
dc.date2026-02-16T05:37:37Z
dc.date2026-02-16T05:37:37Z
dc.date.accessioned2026-06-27T04:12:32Z
dc.descriptionThe food industry generates substantial keratin waste, particularly chicken feathers, which are rich in amino acids and essential nutrients. However, the insolubility of keratin presents a significant challenge to its conversion. Keratinase, an enzyme produced by certain fungi and bacteria, offers a promising solution by degrading feather keratin into amino acids and soluble proteins. Among these, bacterial keratinase is notable for its superior stability and activity, although its production remains constrained, necessitating continued research to identify efficient microbial strains. Keratin-derived hydrolyzates, recognized for their biological and immunological properties, have garnered significant research interest. This review examines the structural characteristics of chicken feather keratin, its resistance to conventional proteases, and advances in keratinase production and purification techniques. Additionally, the keratin degradation mechanism and the adoption of environmentally friendly technologies for managing feather waste are explored. Finally, the review highlights the potential applications of keratinase across diverse industries, including animal feed and cosmetics.
dc.formatapplication/pdf
dc.identifierhttps://hdl.handle.net/10568/181599
dc.identifier.urihttp://hdl.handle.net/123456789/25144
dc.languageen
dc.publisherWiley
dc.rightsOpen Access
dc.sourceMoktip, Thanakorn, Lakha Salaipeth, Ana Eusebio Cope, Mohammad J. Taherzadeh, Takashi Watanabe, and Paripok Phitsuwan (2025). Current Understanding of Feather Keratin and Keratinase and Their Applications in Biotechnology. Biochemistry Research International 2025, no. 1: 6619273.
dc.subjectkeratin
dc.subjectfeathers
dc.subjectpoultry
dc.subjectamino acids
dc.subjectproteases
dc.subjecthydrolysis
dc.subjectbacteria
dc.subjectfungi
dc.subjectanimal feed
dc.titleCurrent Understanding of Feather Keratin and Keratinase and Their Applications in Biotechnology
dc.typeJournal Article

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Instituto Internacional de Investigación del Arroz (IRRI)