Anthelmintic activity of preparations derived from Myrsine africana and Rapanea melanophloeos against the nematode parasite, Haemonchus contortus, of sheep

dc.creatorGithiori, J.B.
dc.creatorHöglund, J.
dc.creatorWaller, P.J.
dc.creatorBaker, R.L.
dc.date2002-05
dc.date2013-05-06T07:01:41Z
dc.date2013-05-06T07:01:41Z
dc.date.accessioned2026-06-27T16:40:55Z
dc.descriptionMyrsine africana L. and Rapanea melanophloeos L. belong to the plant family Myrsinaceae. Various rural communities in Kenya, such as smallholder farmers and pastoralists, use them to treat their livestock. The anthelmintic effects/activities of leaves and fruits of M. africana and fruits of R. melanophloeos were tested in sheep experimentally infected with the nematode parasite Haemonchus contortus. Male lambs were infected with 3000–5000 third stage larvae of H. contortus and treated 28 days after inoculation with concoctions made from leaves or fruits of the plants. No significant reduction in faecal nematode egg counts was observed with any of the concoctions at any of the doses tested. Packed red cell volume decreased and live weight increased at similar rates in treated and control groups, thus there was no significant effect of treatment. The results showed that the tested extracts of the M. africana and R. melanophloeos were not efficacious against H. contortus in sheep.
dc.identifierhttps://hdl.handle.net/10568/28895
dc.identifier.urihttp://hdl.handle.net/123456789/130248
dc.languageen
dc.publisherElsevier
dc.rightsLimited Access
dc.sourceJournal of Ethnopharmacology;80(2-3): 187-191
dc.subjectdrug plants
dc.subjecthaemonchus contortus
dc.subjectsheep
dc.subjectnematoda
dc.subjectanthelmintics
dc.subjecttraditional medicines
dc.subjectmyrsinaceae
dc.subjectpharmacology
dc.titleAnthelmintic activity of preparations derived from Myrsine africana and Rapanea melanophloeos against the nematode parasite, Haemonchus contortus, of sheep
dc.typeJournal Article

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