Endemic stability - a veterinary idea applied to human public health

dc.creator	Coleman, P.G.
dc.creator	Perry, Brian D.
dc.creator	Woolhouse, Mark E.J.
dc.date	2001-04
dc.date	2013-06-11T09:22:38Z
dc.date	2013-06-11T09:22:38Z
dc.date.accessioned	2026-06-27T16:35:22Z
dc.description	Endemic stability is an epidemiological state of a population, in which clinical disease is scarce despite high level of infection. The notion was developed to describe patterns of tick-borne disease in cattle. However, we propose a general, nodes of endemic stability that is applicable to a broader range of diseases that are important in public health, including malaria, rubella, and mumps. We postulate that endemic stability requires only that (1) the probability, or severity, of clinical disease after infection increases with age, and (2) after one infection, the probability that subsequent infections result in disease is reduced. We present these criteria in simple mathematical terms. Our hypothesis predicts that partial disease control activities might, under certain circumstances, lead to an increase in disease incidence. We discuss the implications, for public health interventions.
dc.identifier	https://hdl.handle.net/10568/29165
dc.identifier.uri	http://hdl.handle.net/123456789/127411
dc.language	en
dc.publisher	Elsevier
dc.rights	Limited Access
dc.source	Lancet;357(9264): 1284-1286
dc.subject	endemics
dc.subject	animal diseases
dc.subject	public health
dc.title	Endemic stability - a veterinary idea applied to human public health
dc.type	Journal Article

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