Trypanosoma congolense infection in sheep: Ultrastructural changes in the skin prior to development of local skin reactions

Mwangi, David Miano; Hopkins, J.; Luckins, A.G.

Trypanosoma congolense infection in sheep: Ultrastructural changes in the skin prior to development of local skin reactions

Autores

Mwangi, David Miano

Hopkins, J.

Luckins, A.G.

Editor

Elsevier

Descripción

Events occurring in the skin of sheep prior to development of Trypanosoma congolense-induced local skin reactions (chancres) were studied using electron microscopy. Three days after infection, few trypanosomes were present in the dermal collagen. However, these parasites were more abundant 5 days after infection, and were also found in dermal lymphatics and in the connective tissue matrix between collagen bundles. Mast cells in the skin obtained 5 days after infection showed evidence of degranulation. These events may play a role during the induction phase of trypanosomal chancres.