Strong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays

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dc.creatorRennie, C.
dc.creatorNoyes, H.A.
dc.creatorKemp, Stephen J.
dc.creatorHulme, H.
dc.creatorBrass, A.
dc.creatorHoyle, D.C.
dc.date2008-12
dc.date2010-08-07T12:07:26Z
dc.date2010-08-07T12:07:26Z
dc.date.accessioned2026-06-27T17:09:04Z
dc.descriptionMicroarrays are an important and widely used tool. Applications include capturing genomic DNA for high-throughput sequencing in addition to the traditional monitoring of gene expression and identifying DNA copy number variations. Sequence mismatches between probe and target strands are known to affect the stability of the probe-target duplex, and hence the strength of the observed signals from microarrays.
dc.identifierhttps://hdl.handle.net/10568/2202
dc.identifier.urihttp://hdl.handle.net/123456789/143717
dc.languageen
dc.publisherSpringer
dc.rightsOpen Access
dc.sourceRennie, C.; Noyes, H.A.; Kemp, S.J.; Hulme, H.; Brass, A.; Hoyle, D.C. 2008. Strong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays. BMC Genomics 9:317.
dc.subjectgenetics
dc.subjectlivestock
dc.titleStrong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays
dc.typeJournal Article

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