A life-cycle stage-specific antigen of Theileria parva recognized by anti-macroschizont monoclonal antibodies

Vista sencilla de ítem
dc.creatorShapiro, S.Z.
dc.creatorFujisaki, K.
dc.creatorMorzaria, S.P.
dc.creatorWebster, P.
dc.creatorFujinaga, T.
dc.creatorSpooner, P.R.
dc.creatorIrvin, A.D.
dc.date1987-02
dc.date2013-06-11T09:23:25Z
dc.date2013-06-11T09:23:25Z
dc.date.accessioned2026-06-27T16:31:05Z
dc.descriptionFour monoclonal antibodies, raised against macroschizonts ofTheileria parva, were studied to characterize their antigen binding specificity. The indirect fluorescent antibody test showed that the antigen(s) recognized were present in the macroschizont stage of the parasite life-cycle but not in piroplasm, kinete or sporozoite stages. Immunoblot analysis of macroschizont stage antigens suggested that all four antibodies recognized the same antigen. This was a molecule which varied in molecular mass between different parasite stocks, ranging from 68000 to 95000 Da. The antigen was localized by immunoelectron microscopy to the surface of the intracellular macroschizonts.
dc.identifierhttps://hdl.handle.net/10568/29396
dc.identifier.urihttp://hdl.handle.net/123456789/125135
dc.languageen
dc.publisherCambridge University Press
dc.rightsLimited Access
dc.sourceParasitology;94: 29-37
dc.subjecttheileria parva
dc.subjectmonoclonal antibodies
dc.subjectantigens
dc.subjectantibodies
dc.subjectinfectious diseases
dc.subjectparasitology
dc.titleA life-cycle stage-specific antigen of Theileria parva recognized by anti-macroschizont monoclonal antibodies
dc.typeJournal Article

Archivos

Colecciones

Instituto Internacional de Investigaciones Pecuarias (ILRI)