Chemical composition and anthelmintic activity in vitro of the essential oil of Mentha piperita: preliminary data.

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dc.contributorRaimundo Jeova Martins Mesquita, Instituto Superior de Teologia Aplicada (INTA) - Sobral, CE, Brazil
dc.contributorJOMAR PATRICIO MONTEIRO, CNPC
dc.contributorFrancisco Eduardo Aragão Catunda, Universidade Estadual da Região Tocantina do Maranhão (UEMASUL) - Imperatriz, MA, Brazil
dc.contributorMARCEL TEIXEIRA, CNPC.
dc.creatorMESQUITA, R. J. M.
dc.creatorMONTEIRO, J. P.
dc.creatorCATUNDA, F. E. A.
dc.creatorTEIXEIRA, M.
dc.date2017-11-22T23:19:11Z
dc.date2017-11-22T23:19:11Z
dc.date2017-11-08
dc.date2017
dc.date2019-09-23T11:11:11Z
dc.date.accessioned2026-07-01T00:20:49Z
dc.descriptionAbstract: Research towards plant compounds with activity against worm parasites has been carried out for a number of decades; however it is especially important now when drench resistance has compromised the effectiveness of present control methods. In this study we characterized the composition of Mentha piperita essential oil and evaluated its anthelmintic effect against developmental stages of trichostrongylids from naturally infected goats (95% Haemonchus contortus and 5% Trichostrogylus spp.) through the egg hatch and larval development assays. The major constituent of the tested substance quantified by gas chromatography was menthol (58.35%). The lowest concentration of essential oil with 100% efficacy in all in vitro tests against caprine trichostrongylids was 0.35%. However, the equivalent dose of menthol alone (0.4%) was not fully effective against nematode egg eclosion. The anthelmintic activity of the essential oil of M. piperita showed good effectiveness in previous studies but also showed the presence of toxic compounds such as pulegone which could be toxic to goats according to allometric extrapolation. Our results show that the major component in the essential oil is not the only one responsible for the antiparasitic effect of M. piperita. Also, our data support the idea there is a wide variation in the composition of essential oils obtained from different sources. Thus, it is important that in assessing anthelmintic activity of plant candidates, the chemical composition should be thoroughly investigated before proceeding to the in vivo step.
dc.descriptionIn conjunction with 53rd MSPTM Annual Conference.
dc.identifierIn: INTERNATIONAL CONFERENCE OF THE WORLD ASSOCIATION FOR THE ADVANCEMENT OF VETERINARY PARASITOLOGY, 26., 2017, Kuala Lumpur, Malaysia. Abstract book. Perth: WAAVP, 2017. p. 445. Abstract 4884.
dc.identifierhttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1079264
dc.identifier.urihttp://hdl.handle.net/123456789/402272
dc.languageeng
dc.rightsopenAccess
dc.subjectPulegone
dc.subjectAção antiparasitária
dc.subjectTrichostrogylus
dc.subjectDrug plants
dc.subjectCulinary herbs
dc.subjectCaprino
dc.subjectAnti-helmíntico
dc.subjectÓleo essencial
dc.subjectMenta
dc.subjectExtrato vegetal
dc.subjectPlanta medicinal
dc.subjectFitoterapia
dc.subjectHaemonchus Contortus
dc.subjectMentha
dc.subjectGoats
dc.subjectAnthelmintics
dc.subjectEssential oils
dc.subjectNematoda
dc.subjectTrichostrongylidae
dc.subjectPhytotherapy
dc.titleChemical composition and anthelmintic activity in vitro of the essential oil of Mentha piperita: preliminary data.
dc.typeResumo em anais e proceedings

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