Effects of Mesterolone in the physiology, welfare and masculinization of the neotropical tambaqui Colossoma macropomum.
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For Brazilian aquaculture, tambaqui Colossoma macropomum is the main native species. In farming conditions, females can grow up to 50% more than the males, most likely for entering puberty later than males. As tambaqui sex-determination system is XX/XY, there is the possibility to generate monosex population of females by crossing out normal females with neo-males (genetic females -XX displaying male phenotype). The goal of this study was to invert the sex phenotype of female tambaqui using mesterolone, which is a synthetic androgen derivative of dihydrotestosterone. Since in fish the hematological parameters may alter as a result of pollutants or drugs used in aquaculture, we evaluated the welfare of treated fish through biomarkers of liver function, i. e. biochemical parameters and histopathological analysis of the liver.
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Colossoma Macropomum, Tambaqui