JECFA Toolbox for Veterinary Drug Residues Risk Assessment
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Veterinary drug residues from animal-derived food products may pose risks to human health. To perform a drug residue risk assessment, we must first characterize the risk by evaluating the hazard and assessing exposure. Consult the guidance document for a brief description of the relevant data necessary for the evaluation process, followed by the key outcomes and relevant JECFA experts responsible along each step of the JECFA risk assessment process:• Hazard assessment: Derivation of health-based guidance values (HBGVs) such as acceptable daily intake (ADI) and acute reference dose (ARfD);• Residue assessment: Total residue (TR) and marker residue (MR) depletion in edible tissues;• Exposure assessment: Use of the global estimated chronic or acute dietary intake; and • How maximum residue limits (MRLs) are derived as the final step of the JECFA risk assessment process. This publication is part of the FAO JECFA Toolbox for Veterinary Drug Residue Risk Assessment. The toolbox provides practical guidance on the principles, modalities and technical requirements of JECFA in assessing the risks of veterinary drug residues in food and in recommending MRLs.