Chargaff's "Grammar of Biology": new fractal-like rules.

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dc.contributorMICHEL EDUARDO BELEZA YAMAGISHI, CNPTIA; ROBERTO H. HERAI, University of California San Diego.
dc.creatorYAMAGISHI, M. E. B.
dc.creatorHERAI, R. H.
dc.date2025-07-07T12:50:31Z
dc.date2025-07-07T12:50:31Z
dc.date2014-01-02
dc.date2013
dc.date.accessioned2026-07-07T04:18:13Z
dc.descriptionChargaff once said that "I saw before me in dark contours the beginning of a grammar of Biology?. In linguistics, "grammar" is the set of natural language rules, but we do not know for sure what Chargaff meant by a "grammar" of Biology. Chargaff discovered some rules about nucleotides that have been named Chargaff's rules. In this work, we further develop his "grammar". Using new concepts, we were able to discover new higher order genomic rules that seem to be invariant across a large set of organisms, and show a fractal-like property, since no matter the scale, the same pattern is observed (self-similarity). We hope that these new invariant genomic rules may be used in different contexts, for example for short read data bias detection and genome assembly quality assessment.
dc.descriptionPôster P1003.
dc.formatNão paginado.
dc.identifierIn: INTERNATIONAL PLANT & ANIMAL GENOME, 21., 2013, San Diego. [Abstracts...]. [S.l.: s.n.], 2013.
dc.identifierhttp://www.alice.cnptia.embrapa.br/alice/handle/doc/974768
dc.identifier.urihttp://hdl.handle.net/123456789/457111
dc.languageeng
dc.rightsopenAccess
dc.subjectGenômica
dc.subjectBioinformática
dc.subjectPropriedade fractal
dc.subjectGenomics
dc.subjectBioinformatics
dc.titleChargaff's "Grammar of Biology": new fractal-like rules.
dc.typeResumo em anais e proceedings

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