The effect of Trypanosoma brucei brucei infection on rabbit plasma iron and zinc concentrations

Vista sencilla de ítem
dc.creatorMwangi, S.M.
dc.creatorMcOdimba, F.A.
dc.creatorLogan-Henfrey, L.L.
dc.date1995-08
dc.date2013-05-06T06:59:48Z
dc.date2013-05-06T06:59:48Z
dc.date.accessioned2026-06-27T16:54:31Z
dc.descriptionChanges in plasma iron and zinc concentration were studied in rabbits following a needle challenge with Trypanosoma brucei brucei clone ILTat 2.1. The infection resulted in a decrease of the concentration of both trace elements. Plasma iron concentrations decreased gradually and were decreased maximally to 53.3 percent of pre-infection levels on day 19 post-inoculation. Plasma zinc concentrations, on the other hand, decreased more rapidly and were decreased maximally to 27.4 percent of pre-infection levels on day 3 post-inoculation. The onset of these decreases coincided with the appearance of parasites in the peripheral blood. Furthermore, the magnitude of their decrease correlated closely with the level and duration of the parasitaemia. Other abnormal findings, namely, anaemia and periods of leucocytosis and leukopenia, were also observed. This study therefore demonstrates that depression in plasma iron and zinc concentrations is part of the acute phase response in rabbits infected with this clone of T.b brucei.
dc.identifierhttps://hdl.handle.net/10568/28044
dc.identifier.urihttp://hdl.handle.net/123456789/136769
dc.languageen
dc.publisherElsevier
dc.rightsLimited Access
dc.sourceActa Tropica;59: 283-291
dc.subjecttrypanosoma brucei
dc.subjectrabbits
dc.subjectblood plasma
dc.subjectiron
dc.subjectzinc
dc.titleThe effect of Trypanosoma brucei brucei infection on rabbit plasma iron and zinc concentrations
dc.typeJournal Article

Archivos

Colecciones

Instituto Internacional de Investigaciones Pecuarias (ILRI)