Extreme-QTL mapping of monepantel resistance in Haemonchus contortus.

dc.contributorSIMONE CRISTINA MEO NICIURA, CPPSE; Polyana Cristine Tizioto, NGS Soluções Genômicas; Caroline Valério Moraes, UFSCar; Giovanna Gabrielle Cruvinel, UNICEP; Ana Cláudia Alexandre de Albuquerque, FMVZ-UNESP; RAUL COSTA MASCARENHAS SANTANA, CPPSE; ANA CAROLINA DE SOUZA CHAGAS, CPPSE; SERGIO NOVITA ESTEVES, CPPSE; MAGDA VIEIRA BENAVIDES, CPPSUL; Alessandro Francisco Talamini do Amarante, IBB-UNESP.
dc.creatorNICIURA, S. C. M.
dc.creatorTIZIOTO, P. C.
dc.creatorMORAES, C. V.
dc.creatorCRUVINEL, G. G.
dc.creatorALBUQUERQUE, A. C. A. de
dc.creatorSANTANA, R. C. M.
dc.creatorCHAGAS, A. C. de S.
dc.creatorESTEVES, S. N.
dc.creatorBENAVIDES, M. V.
dc.creatorAMARANTE, A. F. T. do
dc.date2019-08-21T00:38:33Z
dc.date2019-08-21T00:38:33Z
dc.date2019-08-20
dc.date2019
dc.date2019-10-10T11:11:11Z
dc.date.accessioned2026-07-07T05:27:42Z
dc.descriptionHaemonchus contortus, a gastrointestinal nematode parasite of sheep, is mainly controlled by anthelmintics; the occurrence of anthelmintic resistance leads to treatment failures and increases economic burden. Because molecular mechanisms involved in drug resistance can be elucidated by genomic studies, an extreme quantitative trait locus (X-QTL) mapping approach was used to identify co-segregation of the resistance phenotype with genetic markers to detect the genome-wide variants associated with monepantel resistance in H. contortus.
dc.identifierParasites Vectors, v.12, n.403, p.1-11, 2019.
dc.identifierhttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1111456
dc.identifierhttps://doi.org/10.1186/s13071-019-3663-9
dc.identifier.urihttp://hdl.handle.net/123456789/491958
dc.languageeng
dc.rightsopenAccess
dc.subjectAnthelmintic resistance
dc.subjectGenome sequencing
dc.subjectSheep gastrointestinal nematodes
dc.subjectF2 mapping
dc.subjectDrug resistance
dc.titleExtreme-QTL mapping of monepantel resistance in Haemonchus contortus.
dc.typeArtigo de periódico

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