PHOSPHOLIPASE A2 (PLA2) ENZYME PREPARATION FROM STREPTOMYCES VIOLACEORUBER EXPRESSING A GENE ENCODING PLA2 FROM S. VIOLACEORUBER, Chemical and Technical Assessment (CTA), 92nd JECFA

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This Chemical and Technical Assessment summarizes data and information on the Phospholipase A2 (PLA2) enzyme preparation from Streptomyces violaceoruber expressing a PLA2 gene from the same species (PLA2 enzyme preparation) that was submitted to JECFA. This document also discusses published information relevant to the safety of PLA2 enzyme, including the S. violaceoruber production organism and details related to the manufacturing, specifications, use and use levels of the enzyme in food. This document uses the expression “PLA2” to refer to the modified enzyme and its amino acid sequence, and the expression “PLA2 enzyme preparation” to refer to the product formulated for commercial use.

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