Impact of Intermittent Screening and Treatment for Malaria among School Children in Kenya : A Cluster Randomized Trial

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dc.creatorHalliday, Katherine E.
dc.creatorOkello, George
dc.creatorTurner, Elizabeth L.
dc.creatorNjagi, Kiambo
dc.creatorMcharo, Carlos
dc.creatorKengo, Juddy
dc.creatorAllen, Elizabeth
dc.creatorDubeck, Margaret M.
dc.creatorJukes, Matthew C.H.
dc.creatorBrooker, Simon J.
dc.date2014-03-18T21:32:22Z
dc.date2014-03-18T21:32:22Z
dc.date2014-02
dc.date.accessioned2026-07-01T00:48:30Z
dc.descriptionThis paper investigates the effects of intermittent screening and treatment of malaria on the health and education of school children in an area of low-to-moderate malaria transmission. A cluster randomized trial was implemented with 5,233 children in 101 government primary schools on the south coast of Kenya in 2010-12. The intervention was delivered to children randomly selected from classes 1 and 5 who were followed up twice across 24 months. Once during each school term, public health workers used malaria rapid diagnostic tests to screen the children. Children who tested positive were treated with a six-dose regimen of artemether-lumefantrine. Given the nature of the intervention, the trial was not blinded. The primary outcomes were anemia and sustained attention and the secondary outcomes were malaria parasitaemia and educational achievement. The data were analyzed on an intention-to-treat basis. Anemia in this setting in Kenya, intermittent screening and treatment, as implemented in this study, is not effective in improving the health or education of school children. Possible reasons for the absence of an impact are the marked geographical heterogeneity in transmission, the rapid rate of reinfection following artemether-lumefantrine treatment, the variable reliability of malaria rapid diagnostic tests, and the relative contribution of malaria to the etiology of anemia in this setting.
dc.formatapplication/pdf
dc.formattext/plain
dc.identifierhttp://documents.worldbank.org/curated/en/2014/02/19153553/impact-intermittent-screening-treatment-malaria-among-school-children-kenya-cluster-randomized-trial
dc.identifierhttps://hdl.handle.net/10986/17333
dc.identifierhttps://doi.org/10.1596/1813-9450-6791
dc.identifier.urihttp://hdl.handle.net/123456789/411312
dc.languageEnglish
dc.languageen_US
dc.publisherWorld Bank, Washington, DC
dc.relationPolicy Research Working Paper;No. 6791
dc.rightsCC BY 3.0 IGO
dc.rightshttp://creativecommons.org/licenses/by/3.0/igo/
dc.subjectACADEMIC ACHIEVEMENT
dc.subjectACCESS TO FOOD
dc.subjectACCESS TO TREATMENT
dc.subjectACHIEVEMENT
dc.subjectACHIEVEMENT TESTS
dc.subjectADJUSTMENT
dc.subjectADOLESCENTS
dc.subjectAGED
dc.subjectAMODIAQUINE
dc.subjectANEMIA
dc.subjectANEMIA CONTROL
dc.subjectANOPHELES MOSQUITOES
dc.subjectANTENATAL CARE
dc.subjectARITHMETIC
dc.subjectATTENTION
dc.subjectBASIC EDUCATION
dc.subjectBASIC EDUCATION SECTOR
dc.subjectBLIND
dc.subjectBLOOD SAMPLES
dc.subjectBURDEN OF MALARIA
dc.subjectCERVICAL CANCER
dc.subjectCHILD DEVELOPMENT
dc.subjectCHILDHOOD
dc.subjectCLASSROOM
dc.subjectCOGNITION
dc.subjectCOGNITIVE DEVELOPMENT
dc.subjectCOGNITIVE IMPAIRMENT
dc.subjectCOGNITIVE PERFORMANCE
dc.subjectCOMPARATIVE EDUCATION
dc.subjectDEWORMING
dc.subjectDIAGNOSIS
dc.subjectDIAGNOSTIC TESTS
dc.subjectDISEASE
dc.subjectDISEASE BURDEN
dc.subjectDROWNING
dc.subjectDRUG ADMINISTRATION
dc.subjectDRUG RESISTANCE
dc.subjectDRUG TREATMENT
dc.subjectDRUGS
dc.subjectEDUCATIONAL ATTAINMENT
dc.subjectEDUCATIONAL OUTCOMES
dc.subjectEDUCATIONAL PERFORMANCE
dc.subjectEFFECTIVE EDUCATION
dc.subjectEFFECTIVE TEACHING
dc.subjectENROLLMENT
dc.subjectEPIDEMIOLOGY
dc.subjectETHICS
dc.subjectEXAM
dc.subjectFEMALE ADOLESCENTS
dc.subjectFEMALES
dc.subjectFREE SCHOOLS
dc.subjectGAMETOCYTE CARRIAGE
dc.subjectGOVERNMENT PRIMARY SCHOOLS
dc.subjectHEADACHE
dc.subjectHEALTH FACILITY
dc.subjectHEALTH INTERVENTIONS
dc.subjectHEALTH OUTCOMES
dc.subjectHEALTH SURVEYS
dc.subjectHEALTH WORKERS
dc.subjectHEMOGLOBIN CONCENTRATION
dc.subjectHIGH MALARIA TRANSMISSION
dc.subjectHIGH RISK OF INFECTION
dc.subjectHIV
dc.subjectHUMAN BIOLOGY
dc.subjectHYGIENE
dc.subjectIMPACT OF MALARIA
dc.subjectINFANTS
dc.subjectINFECTION
dc.subjectINFECTION RATES
dc.subjectINFECTIONS
dc.subjectINFORMED CONSENT
dc.subjectINTERVENTION
dc.subjectIRON
dc.subjectLEARNING
dc.subjectLEUKEMIA
dc.subjectLITERACY
dc.subjectLITERACY INSTRUCTION
dc.subjectLYMPHATIC FILARIASIS
dc.subjectMALARIA
dc.subjectMALARIA CONTROL
dc.subjectMALARIA DIAGNOSIS
dc.subjectMALARIA ENDEMIC COUNTRIES
dc.subjectMALARIA IN PREGNANCY
dc.subjectMALARIA INFECTION
dc.subjectMALARIA INFECTIONS
dc.subjectMALARIA INTERVENTIONS
dc.subjectMALARIA MORBIDITY
dc.subjectMALARIA PARASITES
dc.subjectMALARIA PREVENTION
dc.subjectMALARIA SYMPTOMS
dc.subjectMALARIA TRANSMISSION
dc.subjectMALARIA TREATMENTS
dc.subjectMALARIA-ENDEMIC AREAS
dc.subjectMASS SCREENING
dc.subjectMEDICAL RESEARCH
dc.subjectMENTAL DEVELOPMENT
dc.subjectMIGRATION
dc.subjectMODELING
dc.subjectMORBIDITY
dc.subjectMORBIDITY AND MORTALITY
dc.subjectMORTALITY
dc.subjectMOSQUITO NET
dc.subjectNATIONAL SURVEILLANCE
dc.subjectNEGATIVE EFFECTS
dc.subjectNUMERACY
dc.subjectNURSES
dc.subjectNUTRITION
dc.subjectNUTRITIONAL STATUS
dc.subjectOLDER CHILDREN
dc.subjectPARASITIC INFECTIONS
dc.subjectPARASITOLOGY
dc.subjectPARENTAL EDUCATION
dc.subjectPNEUMONIA
dc.subjectPOLYMERASE CHAIN REACTION
dc.subjectPREGNANCY
dc.subjectPREGNANT WOMEN
dc.subjectPREVALENCE
dc.subjectPREVENTION OF MALARIA
dc.subjectPREVENTIVE TREATMENT
dc.subjectPRIMARY SCHOOL
dc.subjectPRIMARY SCHOOL ACCESS
dc.subjectPRIMARY SCHOOLING
dc.subjectPRIMARY SCHOOLS
dc.subjectPROPHYLAXIS
dc.subjectPUBLIC HEALTH
dc.subjectSCHOOL HEALTH
dc.subjectSCHOOL QUALITY
dc.subjectSCHOOLING
dc.subjectSCREENING
dc.subjectSEX
dc.subjectSIBLINGS
dc.subjectSOCIAL SCIENCE RESEARCH
dc.subjectSTOMACH
dc.subjectTEACHER EDUCATION
dc.subjectTEACHERS
dc.subjectTEACHING METHODS
dc.subjectTHERAPY
dc.subjectTRAUMA
dc.subjectTREATMENT
dc.subjectTREATMENT OF MALARIA
dc.subjectTROPICAL DISEASES
dc.subjectTROPICAL MEDICINE
dc.subjectVECTORS
dc.subjectVOMITING
dc.subjectWORKERS
dc.subjectYELLOW FEVER
dc.subjectMicrodata Set
dc.titleImpact of Intermittent Screening and Treatment for Malaria among School Children in Kenya : A Cluster Randomized Trial

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