Accumulation of persistent organochlorine contaminants in milk and serum of farmers from Ghana

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dc.creatorNtow, W.J.
dc.creatorTagoe, L.M.
dc.creatorDrechsel, Pay
dc.creatorKelderman, P.
dc.creatorGijzen, H.J.
dc.creatorNyarko, E.
dc.date2008
dc.date2014-06-13T14:48:22Z
dc.date2014-06-13T14:48:22Z
dc.date.accessioned2026-06-27T18:26:07Z
dc.descriptionIn the present study, the concentrations of persistent organochlorine (OC) pesticides such as dichlorodiphenyltrichloroethane and its metabolites (DDTs), hexachlorocyclohexane isomers (HCHs), hexachlorobenzene (HCB) and dieldrin in pooled samples of human breast milk (n ? 109), and serum (n ? 115) from vegetable farmers in Ghana, during 2005, were determined. Gas chromatography with mass spectrometry was used to quantify residue levels on a lipid basis of the OCs. The pattern of OCs in human fluid showed that DDTs was consistently the prevalent OC in milk and blood. The levels of DDTs, HCHs, and dieldrin in the breast milk samples were found to correlate positively with age of the milk sample donors (rs ? 0.606, 0.770, and 0.540, respectively). When blood serum levels of the OCs were compared between male and female farmers, no pronounced relationship for HCHs and HCB (p40.05) was observed. However, DDTs and dieldrin residues were significantly higher (po0.05) in males than in females. There was association between breast milk and serum residues. When daily intakes of DDTs and HCHs to infants through human breast milk were estimated, some individual farmers (in the case of DDTs) and all farmers (in the case of HCHs) accumulated OCs in breast milk above the threshold (tolerable daily intake, TDI, guidelines proposed by Health Canada) for adverse effects, which may raise concern on children health.
dc.identifierhttps://hdl.handle.net/10568/40761
dc.identifier.urihttp://hdl.handle.net/123456789/155743
dc.languageen
dc.rightsLimited Access
dc.sourceNtow, W. J.; Tagoe, L. M.; Drechsel, Pay; Kelderman, P.; Gijzen, H. J.; Nyarko, E. 2008. Accumulation of persistent organochlorine contaminants in milk and serum of farmers from Ghana. Environmental Research, 106: 17?26.
dc.subjectpesticides
dc.subjectorganochlorine compounds
dc.subjectrisks
dc.subjectassessment
dc.subjectfarmers
dc.subjectwomen
dc.subjecthealth hazards
dc.subjectoccupational hazards
dc.titleAccumulation of persistent organochlorine contaminants in milk and serum of farmers from Ghana
dc.typeJournal Article

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Instituto Internacional para el Manejo del Agua (IWMI)