Further development of flexible parametric models for survival analysis

dc.creatorLambert, Paul C.
dc.creatorRoyston, Patrick
dc.date2017-04-01T19:52:06Z
dc.date.accessioned2026-07-09T06:15:38Z
dc.descriptionRoyston and Parmar (2002, Statistics in Medicine 21: 2175–2197) developed a class of flexible parametric survival models that were programmed in Stata with the stpm command (Royston, 2001, Stata Journal 1: 1–28). In this article, we introduce a new command, stpm2, that extends the methodology. New features for stpm2 include improvement in the way time-dependent covariates are modeled, with these effects far less likely to be over parameterized; the ability to incorporate expected mortality and thus fit relative survival models; and a superior predict command that enables simple quantification of differences between any two covariate patterns through calculation of time-dependent hazard ratios, hazard differences, and survival differences. The ideas are illustrated through a study of breast cancer survival and incidence of hip fracture in prostate cancer patients.
dc.identifierOther:st0165
dc.identifierdoi:10.22004/ag.econ.127346
dc.identifierhttps://ageconsearch.umn.edu/record/127346/files/sjart_st0165.pdf
dc.identifierhttp://ageconsearch.umn.edu/record/127346
dc.identifier.urihttp://hdl.handle.net/123456789/574317
dc.languageeng
dc.publisher
dc.sourcehttp://ageconsearch.umn.edu/record/127346
dc.titleFurther development of flexible parametric models for survival analysis
dc.typeText

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