A comprehensive genetic analysis of candidate genes regulating response to Trypanosoma congolense infection in mice

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dc.creatorGoodhead, I.
dc.creatorArchibald, A.L.
dc.creatorAmwayi, P.
dc.creatorBrass, A.
dc.creatorGibson, John P.
dc.creatorHall, N.
dc.creatorHughes, Monica A.
dc.creatorLimo, M.K.H.
dc.creatorIraqi, F.A.
dc.creatorKemp, Stephen J.
dc.creatorNoyes, H.A.
dc.date2010-11-09
dc.date2011-04-17T11:33:58Z
dc.date2011-04-17T11:33:58Z
dc.date.accessioned2026-06-27T16:33:08Z
dc.descriptionAfrican trypanosomes are protozoan parasites that cause “sleeping sickness” in humans and a similar disease in livestock. Trypanosomes also infect laboratory mice and three major quantitative trait loci (QTL) that regulate survival time after infection with T. congolense have been identified in two independent crosses between susceptible A/J and BALB/c mice, and the resistant C57BL/6. These were designated Tir1, Tir2 and Tir3 for Trypanosoma infection response, and range in size from 0.9–12 cM.
dc.identifierhttps://hdl.handle.net/10568/3500
dc.identifier.urihttp://hdl.handle.net/123456789/126268
dc.languageen
dc.publisherPublic Library of Science
dc.rightsOpen Access
dc.sourceGoodhead, I., Archibald, A., Amwayi, P., Brass, A., Gibson, J., Hall, N., Hughes, M.A., Limo, M., Iraqi, F., Kemp, S.J. and Noyes, H.A. 2010. A comprehensive genetic analysis of candidate genes regulating response to Trypanosoma congolense infection in mice. PLoS Neglected Tropical Diseases 4(11):e880.
dc.subjecttrypanosomiasis
dc.subjectinfectious diseases
dc.titleA comprehensive genetic analysis of candidate genes regulating response to Trypanosoma congolense infection in mice
dc.typeJournal Article

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Instituto Internacional de Investigaciones Pecuarias (ILRI)