Newcastle disease virus vaccine strains: immunogenicity is not influenced by ICPI

Vista sencilla de ítem
dc.creatorMA Orsi
dc.creatorL Doretto Júnior
dc.creatorD Reischak
dc.creatorLHA da Silva
dc.creatorFR Spilki
dc.creatorMG Buzinaro
dc.creatorCW Arns
dc.date2009
dc.date.accessioned2026-07-07T03:23:16Z
dc.descriptionIntracerebral pathogenicity index (ICPI) and mean death time (MDT) were determined using commercial live vaccines against Newcastle disease available in Brazil. The ICPI profiles obtained for B1 vaccine strains were nonvirulent and varied from 0 to 0.19, and their MDT was 104-116 hours. The LaSota strains had an ICPI varying between 0.02 and 0.37 and MDT from 92 to 116 hours. ICPI and MDT for the Clone 30 were 0.11 and 104 hours, respectively. For Ulster vaccines, ICPI and MDT were 0 and >150 hours; for VG-GA was 0.03 and 140 hours; and for C2, 0.04 and >144 hours. Eye drop vaccination and IM challenge, at the 1st week and the 4th week, respectively, resulted in highest protection for B1 (95-100%) and LaSota (90-100%) strains. The variability in vaccine ICPI did not interfere with immune response and all vaccines provided similar protection. All vaccines were considered non virulent and were classified as lentogenic according to the immunobiological product standards.
dc.formatapplication/pdf
dc.identifier1516-635X
dc.identifierhttps://www.redalyc.org/articulo.oa?id=179713994009
dc.identifier.urihttp://hdl.handle.net/123456789/432343
dc.languageen
dc.publisherFundação APINCO de Ciência e Tecnologia Avícolas
dc.relationhttp://www.redalyc.org/revista.oa?id=1797
dc.rightsRevista Brasileira de Ciência Avícola
dc.sourceRevista Brasileira de Ciência Avícola (Brasil) Num.2 Vol.11
dc.subjectAgrociencias
dc.titleNewcastle disease virus vaccine strains: immunogenicity is not influenced by ICPI
dc.typeartículo científico

Archivos

Colecciones

Revista Brasileira de Ciência Avícola - Fundação APINCO de Ciência e Tecnologia Avícolas