Area-wide appraisal of drug resistance in trypanosomes infecting cattle in East and Southern Africa
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European Union
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The extent and significance of trypanocidal drug resistance was investigated in priority areas of three East and Southern African Countries under a project. The project was built on the results of two previous projects. Existing methods currently available for the demonstration of drug-resistance, namely therapeutic tests in domestic livestock and rodents, and tests on trypanosome isolates in vitro, have particular drawbacks. In this project, these were supplemented with a novel approach, the use of ELISAs able to quantify the concentrations of trypanocidal drugs circulating in treated cattle.
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trypanosomes (phytomonas), drug resistance, cattle